Explore the Fundamentals of Ion-Exchange SPE and Improve Analyte Recoveries
Ion-exchange solid phase extraction (SPE) is a world of opposites, which at its foundation is based on pairing target analytes with SPE sorbents of the opposite charge and ionic character. This is not always as simple as it sounds, so this ChromaBLOGraphy article uses a series of examples to explore the fundamentals of ion-exchange SPE and to explain how to select the SPE sorbent that will give the best recoveries under different scenarios.