Using Void Volume to Ensure Adequate LC Retention

Ensure Adequate LC Retention by Determining Column Void Volume

When scouting LC columns for method development, it is important to know the column’s void volume because it affects whether early eluting compounds will be adequately retained. Here, we discuss how to determine void volume and retention so that your method will perform well when applied to sample matrix.

Neonicotinoid Insecticides and Honey Bee Health: What’s in Your Honey?

Many governments have limited or banned neonicotinoid insecticides due to potential toxicity to honey bees, whose role as pollinators is critical to global food production. Curious to see if neonicotinoids were in grocery store honey, we developed a QuEChERS and LC-MS/MS workflow, and here’s what we found…

An Introduction to Low-Pressure GC-MS (LPGC-MS)

In our last issue of the Restek Advantage, we demonstrated how low-pressure GC-MS can speed up pesticide analysis in food threefold. Today, we are sharing the background for this innovative technology and explaining how it works and why a new simplified setup makes it more accessible for routine analysis.

PFAS LC Column Anatomy: Which Phase, Dimensions, and Particle Types Are Best?

PFAS analysis became much more challenging after PFOS and PFOA were banned in the EU and replaced with other PFAS products. This guide explores the impact of LC column phase, dimensions, and particle types and gives recommendations on which columns will perform best for different aspects of PFAS analysis.