Solid Phase Extraction: Make the Best Choice for Your Sample

Solid Phase Extraction: Make the Best Choice for Your Sample

Being able to analyze every sample accurately and precisely without sample preparation would be ideal. Yet, this rarely happens—and when faced with a particularly complex matrix and/or analytes present at very low concentrations, dilution is not an option: more active sample preparation steps are needed.

This article discusses how to make the best solid phase extraction (SPE) choice for your sample and analytical goals. It covers the basic principles of SPE, its main separation mechanisms, typical objectives and strategies, formats and characteristics, and method development and cross-referencing.

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