Separation is the foundation of SPE

Solid Phase Extraction: Separation is the Foundation!

Did you know that the same principles that govern liquid chromatography separations are also at play in solid phase extraction (SPE)? In this blog, we explain how two common characteristics—polarity and charge state—can be used to optimize SPE separations. Understanding the polarity and charge of your analytes is one of the easiest ways to determine which SPE stationary and mobile phases will perform best for your target compounds.