Can analyte protectants and matrix help improve peak shapes?

Can Analyte Protectants and Matrix Help Improve Peak Shapes?

Recently, in our LPGC research, we encountered peak splitting and distorted shapes for some early eluting pesticides. Temperature had already been optimized, so we explored the impact of adding analyte protectants vs. matrix on peak shape. Here’s what we found.

Not All Matrix-Matched Calibration Standards Produce the Same Results

Matrix-matched calibrations are a popular option for complex food matrices. But are all matrix-matched calibrations equal? Here, we explore what happens when standards are prepared by spiking spinach prior to extraction vs. spiking cleaned extract right before analysis.

QuEChERS Optimization for Low-Moisture Matrices

Hydration is essential for QuEChERS extraction of low-moisture commodities, but what’s the best water-to-matrix ratio? In this study of honey and brown rice flour, we found that reducing the matrix load below 1:1 may improve sample handling and result in better recoveries.

Fast, Direct Analysis of Underivatized Amino Acids in Infant Formula

Reliable methods for free amino acids in baby food are needed to ensure that nutritional requirements are met. This direct analysis of underivatized amino acids provides excellent results in a faster, easier workflow compared to derivatization-based approaches.