13-Minute, Comprehensive, Direct Analysis of Amino Acids in Plasma
This LC-MS/MS method demonstrated that 45 amino acids could be simultaneously measured in plasma—without derivatization—using a Raptor Polar X column. Acceptable accuracy, precision, and linearity results were obtained in a fast, 13-minute run, making this approach suitable for high-throughput labs.
Fast, 3.5 Minute Analysis of Psilocin and Psilocybin in Urine by LC-MS/MS
In this rapid analysis of psilocin and psilocybin in urine, supernatant from a simple protein precipitation was analyzed directly (no derivatization). Good quantitative results were obtained for linearity, accuracy, precision, and robustness in just 3.5 minutes. These compounds were also added to an established, 231-drug method to improve lab efficiency.
Simplify Alcohol Analyses with Application-Designed GC and LC Columns
On the surface, alcohol analyses appear to be relatively straightforward, but matrix interferences complicate identification and quantitation. Using GC and LC columns designed specifically to lessen the impact of biological interferences can help labs develop methods faster and keep instruments running longer.
Improved Screening Method for Acylcarnitines and Amino Acids
This fast, single-step extraction LC-MS/MS assay provides reliable separation of 22 acylcarnitines and 13 amino acids in dried blood spots. With a fast, 1.2 min run and no derivatization, this approach offers the speed of flow injection methods with improved sensitivity and specificity.