Integrating Ultrashort-Chain Compounds into Human PFAS Biomonitoring
Monitoring ultrashort-chain (C1 to C3) PFAS is essential for tracking human exposure and health consequences, but a lack of analytical methods has limited testing efforts. This new LC-MS/MS method allows testing of C1 to C10 carboxylic and sulfonic acid PFAS, along with four alternative compounds, in human plasma and serum.
- Simultaneous analysis of emerging ultrashort-chain PFAS and established longer chain PFAS.
- Polar-embedded Ultra IBD column provides strong retention of early eluting, polar PFAS, minimizing matrix effects and improving accuracy.
- Single-step protein precipitation sample prep minimizes contamination and eliminates the need for further sample cleanup.